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The FUTURA system is a robotic-assisted platform designed for Ultrasound-guided High Intensity Focused Ultrasound (HIFU) treatment. The control of two independent anthropomorphic manipulators provides the FUTURA platform with high flexibility in terms of operating workspace and maneuverability.The platform is composed of: i) a robotic module, ii) a therapeutic module, and iii) a monitoring module. The robotic module is composed by two anthropomorphic industrial manipulators (i.e., ABB IRB 120) equipped with two force/torque sensors (ATI mini 45). The monitoring module is composed by two different US probes: i) a 2D imaging US probe (Analogic Ultrasound PA7-4/12) confocal to the HIFU transducer, and ii) a motorized 3D imaging US probe (Analogic Ultrasound 4DC7-3/40) mounted on the second manipulator, both connected to the Analogic Ultrasound SonixTablet machine. The therapeutic module consists of a custom-made Focused Ultrasound System. This system has three main components: i) a multi-channel high power signal generator (Image Guided Therapy), ii) a 16 channels phased annular array transducer (Imasonic), and iii) a coupling system (small pillow filled with water) which provides a good acoustic path between the transducer and the patient. The remote control on the FUS generator allows to adjusts the shooting parameters (e.g. focal depth) with a frequency of 20 Hz. The different modules of the FUTURA platform are mutually controlled through dedicated software developed in Robot Operating System (ROS) framework. The FUS treatment is managed by the users through a dedicated Human Machine Interface with real-time visualization of the working scenario. The high modularity of the platform allows for the testing of different modalities: specific experiments dedicated to image guidance, force controlled contact with human tissues, obstacle avoidance strategies between manipulators and patients/operators can be also set-up in the framework of the overall structure.